Overview

Retatrutide is a single synthetic peptide with agonist activity at three class B G-protein-coupled receptors: GIPR, GLP-1R and GCGR. A fatty-acid moiety extends its stability.

In the laboratory it is used in receptor-activation, cAMP-signalling and receptor-selectivity assays in recombinant cell lines. No claims are made regarding effects in humans or animals.

Typical in-vitro applications

• GIPR / GLP-1R / GCGR activation assays (cAMP readout)
• Receptor-selectivity and potency profiling
• Lipidated-peptide stability and analytical method development

Compound data

• Compound: Retatrutide
• Compound class: Acylated triple-agonist peptide
• Receptor class: GIP, GLP-1 and glucagon receptors
• Net content: 10 mg per vial (stated for analytical and preparative calculations)
• Purity specification: ≥99% (HPLC); measured value on the lot certificate of analysis
• Form: Lyophilised powder
• Intended use: In-vitro laboratory research only

Storage & handling

• Store the sealed vial at −20 °C, dry and protected from light.
• Allow the vial to reach room temperature before opening to avoid condensation.
• Handle with standard laboratory protective equipment (gloves, lab coat, eye protection).
• Shipped at ambient temperature in insulated, tamper-evident packaging.

Analytical documentation

HPLC purity and LC-MS identity are tested for every lot. Certificates of analysis and third-party test reports are published in our COA library on the About Us page.

For laboratory research use only. Not for human or veterinary use. See our Research Use Disclaimer.