Overview

SS-31 is an aromatic-cationic tetrapeptide containing D-arginine and 2′,6′-dimethyltyrosine. It is described as binding cardiolipin in the inner mitochondrial membrane.

In the laboratory it is used in isolated-mitochondria and cell-culture assays of cardiolipin interaction, electron transport and reactive-oxygen-species production. No claims are made regarding effects in humans or animals.

Typical in-vitro applications

• Cardiolipin-binding studies
• Mitochondrial respiration and ROS assays
• Membrane-localisation imaging studies

Compound data

• Compound: SS-31
• Compound class: Synthetic tetrapeptide
• Sequence: D-Arg-Dmt-Lys-Phe-NH₂
• Net content: 10 mg per vial (stated for analytical and preparative calculations)
• Purity specification: ≥99% (HPLC); measured value on the lot certificate of analysis
• Form: Lyophilised powder
• Intended use: In-vitro laboratory research only

Storage & handling

• Store the sealed vial at −20 °C, dry and protected from light.
• Allow the vial to reach room temperature before opening to avoid condensation.
• Handle with standard laboratory protective equipment (gloves, lab coat, eye protection).
• Shipped at ambient temperature in insulated, tamper-evident packaging.

Analytical documentation

HPLC purity and LC-MS identity are tested for every lot. Certificates of analysis and third-party test reports are published in our COA library on the About Us page.

For laboratory research use only. Not for human or veterinary use. See our Research Use Disclaimer.