Overview

GHK-Cu is a copper(II) complex of the tripeptide Gly-His-Lys, which occurs naturally in plasma. The peptide binds Cu²⁺ with high affinity and is studied as a copper-transport and signalling molecule.

In the laboratory it is used in fibroblast cell-culture models of collagen and extracellular-matrix synthesis and in gene-expression profiling. No claims are made regarding effects in humans or animals.

Typical in-vitro applications

• Collagen and ECM synthesis assays in fibroblast culture
• Copper–peptide coordination studies
• Gene-expression profiling in cell culture

Compound data

• Compound: GHK-Cu (Gly-His-Lys copper(II) complex)
• Compound class: Copper–tripeptide complex
• Sequence: Gly-His-Lys · Cu²⁺
• Net content: 50 mg per vial (stated for analytical and preparative calculations)
• Purity specification: ≥99% (HPLC); measured value on the lot certificate of analysis
• Form: Lyophilised powder
• Intended use: In-vitro laboratory research only

Storage & handling

• Store the sealed vial at −20 °C, dry and protected from light.
• Allow the vial to reach room temperature before opening to avoid condensation.
• Handle with standard laboratory protective equipment (gloves, lab coat, eye protection).
• Shipped at ambient temperature in insulated, tamper-evident packaging.

Analytical documentation

HPLC purity and LC-MS identity are tested for every lot. Certificates of analysis and third-party test reports are published in our COA library on the About Us page.

For laboratory research use only. Not for human or veterinary use. See our Research Use Disclaimer.